Tadalafil belongs to the group of medicines called phosphodiesterase type 5 (PDE 5) inhibitors, primarily used to treat erectile dysfunction (impotence) and benign prostatic hyperplasia (BPH). Erectile dysfunction is the inability to keep a hard and erect penis suitable for sexual activity. Benign prostatic hyperplasia, also called prostate enlargement, is the non-cancerous growth of the prostate gland.
Tadalafil contains ‘Tadalafil’, which works by relaxing the blood vessels in the penis; this allows the blood to flow into the penis when the person is sexually excited. Thereby, it helps to treat erectile dysfunction. Tadalafil relaxes the bladder and prostate muscles, thereby reducing enlarged prostate symptoms such as difficulty in urination and urgent need to urinate.
You are advised to take Tadalafil for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as headache, back pain, muscle pain, pain in the legs and arms, nasal congestion, indigestion, and facial flushing. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not take Tadalafil if you are taking nitrates (used to treat angina), riociguat (used to treat pulmonary hypertension) or alpha-blockers; if you have heart problems or stroke, low blood pressure or uncontrolled high blood pressure. Tadalafil is not intended for use in women. Tadalafil may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Tadalafil should not be given to children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and the medicines you are taking to avoid unpleasant side effects.
Read the leaflet provided with this medicine for further adviceIf you take Tadalafil for erectile dysfunction, your doctor may prescribe another medicine that contains Tadalafil. However, not everyone taking this medicine takes Tadalafil, and the doctor may adjust the dose of Tadalafil or the dose of other medicines that treat erectile dysfunction.
If you are taking alpha-blocker or nitrates used to treat ( chest pain, angina or heart failure “). You may take this medicine if you are taking riociguat (Adempas) or a Thesei3 medicine if you are taking ritonavir (Aldopam+ACnes) if you are taking this medicine.
Tadalafil may be prescribed for other medical conditions as well:
If you experience any of the following symptoms, stop taking Tadalafil and seek medical help immediately: allergic reactions, chest pain, persistent nausea or vomiting, persistent dizziness, faint or breathing problems, loss of vision, severe dizziness, or yellowing of the skin or eyes. These may returned to a low level on the questionnaire. If you experience severe side effects such as sudden vision loss, chest pain, irregular heartbeat, or chest pain and heart failure.
Long-term effects of TadalafilTake this medicine for as long as your doctor has prescribed it for you, depending on the side effects. Most of the side effects do not require medical attention and will go away gradually over time. However, you are advised to talk to your doctor if you experience long-lasting side effects persistently.The doctor may adjust the dose of Tadalafil or the other medicines that treat erectile dysfunction. If you take Tadalafil for benign prostatic hyperplasia (BPH) you may take a medicine that contains Tadalafil, but you also take a medicine that contains Dapoxetine (‘andy’).
A trusted, FDA-approved oral medication designed to treat erectile dysfunction (ED), tadalafil is a popular choice among men seeking to improve their sexual performance and overall health. It's also effective for pulmonary arterial hypertension (PAH) and certain types of high blood pressure.
Tadalafil tablets are formulated with a combination of tadalafil citrate and sildenafil citrate, the active ingredients responsible for its potent and long-lasting effects. Tadalafil is used for ED and PAH treatment, specifically treating pulmonary arterial hypertension.
Tadalafil tablets can help improve blood flow, which is crucial for achieving and maintaining an erection. Its ability to penetrate the blood vessels, making it a powerful solution for men experiencing ED and PAH.
In this article, we will explore how Tadalafil tablets work, its benefits and considerations, as well as discuss potential side effects and usage precautions.
Tadalafil, a brand name for tadalafil, is a prescription medication that belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It is used to treat erectile dysfunction (ED) in men, PAH in women and benign prostatic hyperplasia (BPH).
Tadalafil works by increasing blood flow to the penis, helping to achieve and maintain an erection. This mechanism helps men achieve and sustain an erection when sexually aroused.
Tadalafil tablets are a phosphodiesterase type 5 (PDE5) inhibitor. They work by relaxing the blood vessels in the penis, allowing increased blood flow. This helps men achieve and sustain an erection when sexually aroused.
Tadalafil works by inhibiting the enzyme PDE5, which is responsible for breaking down cyclic guanosine monophosphate (cGMP). This allows cGMP to accumulate in the corpus cavernosum, leading to smooth muscle relaxation. This increase in blood flow helps men achieve and maintain an erection.
Before starting any treatment for ED or PAH, it's essential to consult with a healthcare provider to ensure the medication is appropriate and safe for your individual needs.
Tadalafil tablets are typically taken as needed, approximately 30 minutes before sexual activity. It is essential to take the medication at the same time each day to maintain consistent levels of the medication in your system.
Tadalafil tablets come in strengths, ranging from 20 mg to 100 mg. The recommended starting dose is usually 2.5 mg taken before sexual activity, allowing for a steady state of effectiveness.
The recommended dosage for ED and PAH treatment is typically prescribed as directed by your healthcare provider, typically 2.5 mg or 5 mg taken at least 30 minutes before engaging in sexual activity. However, it's crucial to follow the prescribed dosing schedule and not exceed the recommended dose.
Tadalafil can be taken with or without food, but it's essential to complete the full course of treatment to ensure its efficacy. It's also important to avoid excessive alcohol consumption, as it can increase the risk of side effects.
Tadalafil is generally well-tolerated, but it's essential to be aware of the potential side effects. Common side effects may include headache, dizziness, flushing, or nasal congestion. More serious but less common side effects are more rare but should be reported to a healthcare provider promptly.
Inform your healthcare provider if you experience any concerning symptoms or allergic reactions. If you have severe liver or kidney problems or if you have recently had a heart attack, signs of irregular heartbeat, or muscle aches, it's essential to seek medical attention.
Tadalafil tablets come in the recommended starting dose range of 2.5 mg to 20 mg. Depending on individual response, the dose may be gradually increased to 5 mg or decreased to 2.5 mg. It's essential to follow your healthcare provider's instructions and avoid excessive alcohol consumption.
Before we explain how Tadalafil helps manage ED, we need to explain how erections occur naturally. When you become aroused, your body releases a substance called nitric oxide (NO). In turn, levels of a chemical known as cyclic guanosine monophosphate (cGMP) increase in your body, relaxing the muscles on the sides of your penis so blood can flow into the organ and trigger a stiff erection.
While all this is happening, your body also compresses the veins that take blood away from the penis, so that the blood remains in place and you can maintain that erection. Eventually, the PDE5 enzyme in your body gets to work, and it processes the cGMP. When that happens, your erection dissipates, and the penis becomes flaccid once again.
If you have ED, regardless of the underlying cause, this natural process is somehow interrupted. That makes it more difficult for you to get or maintain an erection that’s sufficient for intercourse. And that’s where Tadalafil, a PDE5 inhibitor, can help. By blocking this enzyme in your body, you’ll have an easier time getting an erection and holding on to it until sex is complete.
As we mentioned, ED is caused by several factors, and all of them can affect the ability of your body to create an erection.
If you’re prescribed Tadalafil, your doctor will start you on a low dose and gradually increase your dose.
If the dose doesn’t go as high, your doctor may increase the dose to a maximum recommended dose of 10 mg. This is because some patients will experience an increase in the dose but not the maximum dose, so the doctor may need to increase the dose to a 10 mg dose to try and avoid any potential complications.
If the dose doesn’t go as high, your doctor may increase the dose to a maximum dose of 20 mg.
If the dose does go up, it’ll be safe to take it for a longer time than sex. If the dose doesn’t go up, you’ll get an allergic reaction, and your doctor may decide to increase the dose to a maximum dose of 30 mg.
If you get an erection that lasts more than 28 days, you should stop taking Tadalafil and see your doctor immediately.
How Tadalafil Works with Other Erectile Dysfunction IssuesThe other two medications that Tadalafil is prescribed for are Cialis (tadalafil) and Levitra (vardenafil). And because ED is a result of multiple factors, each one can have its own needs and preferences, it is important to understand what each of these two medications is and how it applies to you.
Tadalafil vs Cialis (tadalafil) : What is Tadalafil and How Does Tadalafil Work?Cialis and Levitra both work by relaxing the muscles in the penis, allowing blood to flow into the organ and trigger a stiff erection when you get sexually excited.
These medications treat ED by increasing blood flow to the organ, which can help minimize the discomfort you might experience when you first start taking them.
If you’re diagnosed with erectile dysfunction and experiencing symptoms such as low sex drive, difficulty getting an erection, or if you have other underlying health conditions, we’d love to be able to provide you with a thorough diagnosis.
If you’re prescribed Tadalafil, your doctor will start you on a low dose and gradually increase your dose, usually 10 mg once a day. This is because some patients will experience an increase in the dose but not the maximum dose, so the doctor will need to increase the dose to a maximum of 20 mg once a day.
If the dose didn’t go as high, you’ll get an allergic reaction, and your doctor will increase the dose to a maximum of 30 mg.
If you get an erection that lasts more than 28 days, you’ll need to stop taking Tadalafil and see a doctor immediately.
If you’re prescribed Cialis (tadalafil), your doctor will start you on a low dose and gradually increase your dose, usually 10 mg once a day.
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2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/
3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf
4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36
5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs
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